Medical student Amy Brenner is spending the night on a locked psychiatric ward. Amy has been dreading her evening working on Ward D, the hospital's inpatient mental health unit. There are very specific reasons why she never wanted to do this required overnight rotation. Reasons nobody can ever find out. And as the hours tick by, Amy grows increasingly convinced something terrible is happening within these tightly secured walls. When patients and staff...

Returning to Rio de Janeiro, Dr. Nise Da Silveira returns to work in a psychiatric hospital on the outskirts of the city where she refuses to employ the new and violent electroshock in the treatment of schizophrenics. Ridiculed by doctors, she is forced to take on the abandoned Sector for Occupational Therapy, where she would start a revolution through painting, animals and love.

When fulfilling her father's dying wish leads to a chain of unexpected events, including her husband's suicide, Laura begins to discover secrets in her family's past.