Preface: Manic Depression or Bipolar Disorder? xv --
1 Dimensions of Manic-Depressive Illness 1 --
How Many People in the United States Have Manic-Depressive Illness? 2 --
How Many People Are Being Treated? 4 --
Do Some Groups Have More Than Others? The Hutterites and the Amish 5 --
What Is the Prevalence of Manic-Depressive Illness in Other Countries? 8 --
Has Manic-Depressive Illness Always Existed? 9 --
Is Manic-Depressive Illness Increasing? 13 --
What Is the Cost of Manic-Depressive Illness? 15 --
2 Inner World: Mania and Depression From the Inside 19 --
Awareness of Illness 41 --
3 Outer Worlds: Manic-Depressive Illness Defined 45 --
Are Unipolar Depression and Manic-Depressive Illness One Disease or Two? 52 --
Where Does Manic-Depressive Illness End and Normal Mood Swings Begin? 56 --
What Is the Relationship of Manic-Depressive Illness to Schizoaffective Disorder and Schizophrenia? 57 --
4 Conditions Sometimes Confused with Manic-Depressive Illness 63 --
Mania Caused by Street Drugs 63 --
Mania Caused by Prescription, Over-the-Counter, and Herbal medications 67 --
Mania Caused by Infections 70 --
Mania Caused by Head Injuries 72 --
Mania Associated with Other Brain Disorders 74 --
Mania Associated with Other Illnesses 75 --
What Does Secondary Mania Tell Us About Brain Localization? 76 --
Manic-Like Behavior in Culture-Bound Syndromes 77 --
What Is an Adequate Diagnostic Workup? 78 --
5 Risk Factors for Developing Manic-Depressive Illness 83 --
Pregnancy and Birth Complications 88 --
Severe Stressors in Childhood 90 --
6 Onset, Course, and Outcome 95 --
Factors Affecting Course 96 --
Rapid Cycling and Seasonal Affective Disorder 98 --
Outcomes and Their Predictors 100 --
Stress as a Risk Factor for Relapse 103 --
Studies of Brain Structure 108 --
Studies of Brain Function 113 --
Neurochemical Studies 121 --
Studies of Infections and Immunological Factors 126 --
Disturbances in Body Rhythms 129 --
Endocrine Dysfunction 130 --
Kindling and Stress 133 --
8 Medications: Mood Stabilizers 137 --
Valproate (Depakote, Depakene) 149 --
Carbamazepine (Tegretol) 151 --
Lamotrigine (Lamictal) 154 --
Topiramate (Topamax) 157 --
Gabapentin (Neurontin) 158 --
Calcium Channel Blockers 159 --
Essential Fatty Acids 161 --
9 Medications: Antidepressants, Antipsychotics, and Benzodiazapines 163 --
10 Medications: Treatment Strategies 189 --
Treatments for the Different Phases of Manic-Depressive Illness 189 --
Frequently Asked Questions About Medications 192 --
11 Nonmedication Aspects of Treatment 203 --
Finding a Good Doctor 203 --
Building a Support Network 206 --
Electroconvulsive Therapy 214 --
12 Manic-Depressive Illness in Children and Adolescents 221 --
Diagnostic Aspects 225 --
13 Ten Special Problems 233 --
Concurrent Alcohol and Drug Abuse 233 --
Assaultive and Violent Behavior 237 --
Medication Noncompliance 240 --
Assisted Treatment 244 --
Arrests and Jailings 251 --
Seduction of Mania 263 --
14 Manic-Depressive Illness and Creativity 267 --
Biographical Studies of Mental Illness in Creative People 269 --
Studies of Psychiatric Illness in Living Artists 272 --
Mental Illness and Creativity in Relatives 274 --
Direct Measurements of Creativity in People with Mental Illness 275 --
Effects of Psychotropic Medications on Creativity 276 --
15 Commonly Asked Questions 279 --
Should I Tell People? 279 --
What Are the Chances That Other Family Members Will Get Manic-Depressive Illness? 281 --
How Does It Affect Family Members? 283 --
How Does It Affect Siblings? 286 --
How Does It Affect Spouses? 287 --
How Does It Affect Children? 288 --
16 Issues for Advocates 293 --
Advocacy Organizations 294 --
Scientologists, Antipsychiatrists, and "Consumer Survivors" 295 --
Research Funding and the National Institute of Mental Health 297 --
Stigma and Public Education 299 --
Exemplary Individual Advocates 301.
